The table below lists articles in peer-reviewed journals authored by ACCRF-funded investigators.
| Date | ACCRF PI(s) | Title/Subject | Journal | PubMed |
|---|---|---|---|---|
| 2019 Sep 4 | Morris, Chan, Schultz, Ho, Weigelt, Reis-Filho, El-Naggar, Futreal, Agrawal, Ha | Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma. | J Clin Invest | 31483290 |
| 2013 Sep 15 | Moskaluk | Sinonasal tract and nasopharyngeal adenoid cystic carcinoma: a clinicopathologic and immunophenotypic study of 86 cases. | Head Neck Pathol | 24037641 |
| 2017 Sep 14 | Ferrarotto | Taking it up a NOTCH: a novel subgroup of ACC is identified. | Oncotarget | 29137213 |
| 2018 Sep 12 | Zon, Knoechel, Wick | Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma. | J Exp Med | 30209067 |
| 2017 Sep 12 | Agarwal, Moskaluk, Wick | A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug. | Sci Rep | 28900283 |
| 2016 Sep 10 | Faquin | Fine-Needle Aspiration of Epithelial-Myoepithelial Carcinoma of the Parotid Gland With Prominent Adenoid Cystic Carcinoma-Like Cribriform Features: Avoiding a Diagnostic Pitfall. | Am J Clin Pathol | 27614667 |
| 2013 Sep 1 | Nor | Salivary gland cancer stem cells. | Oral Oncol | 23810400 |
| 2011 Sep 1 | Moskaluk, Stenman | Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms. | Mod Pathol | 21572406 |
| 2013 Aug 8 | Yarbrough | TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. | Oncogene | 23027130 |
| 2016 Aug 5 | Weigelt, Reis-Filho | Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer. | Mod Pathol | 27491809 |
| 2016 Aug 4 | Yarbrough, Ivanov | Clinical and molecular insights into adenoid cystic carcinoma: Neural crest-like stemness as a target. | Laryngoscope Investig Otolaryngol | 28894804 |
| 2009 Aug 26 | Kirsch | Perineural invasion detected by high-field 3.0-T magnetic resonance imaging. | Am J Otolaryngol | 20015797 |
| 2012 Aug 15 | El-Naggar | A comparison of the demographics, clinical features, and survival of patients with adenoid cystic carcinoma of major and minor salivary glands versus less common sites within the Surveillance, Epidemiology, and End Results registry. | Cancer | 22179977 |
| 2008 Aug 15 | El-Naggar | Deletion of 1p32-p36 is the most frequent genetic change and poor prognostic marker in adenoid cystic carcinoma of the salivary glands. | Clin Cancer Res | 18698036 |
| 2016 Aug 1 | Sala | Cutaneous cylindroma: it’s all about MYB. | Cancer Immunol Res | 27185061 |
| 2016 Aug 1 | Schoenfeld, Dranoff, El-Naggar | Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes. | Cancer Immunol Res | 27312343 |
| 2014 Aug 1 | Stenman | Diagnostic and therapeutic implications of new molecular biomarkers in salivary gland cancers. | Oral Oncol | 24856188 |
| 2013 Aug 1 | El-Naggar, Stenman | The 3rd Salivary Gland Tumor Workshop meeting report. | Head Neck | 23677839 |
| 2012 Aug 1 | Stenman | Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma. | Genes Chromosomes Cancer | 22505352 |
| 2010 Aug 1 | Stenman | New tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancer. | Cell Cycle | 20647765 |
| 2011 Jul 28 | El-Naggar | Developmental transcription factor EN1-a novel biomarker in human salivary gland adenoid cystic carcinoma | Cancer | 21800291 |
| 2013 Jul 23 | Yarbrough, Ivanov | Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas. | Br J Cancer | 23799842 |
| 2016 Jul 21 | Morris, Ho, Chan | The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform. | JAMA Oncol | 27442865 |
| 2019 Jul 10 | Ramsay | First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427). | Contemp Clin Trials Commun | 31650066 |
| 2016 Jul 1 | Ha, Wick, Fertig, Brait | Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening. | Int J Oncol | 27212063 |
| 2013 Jul 1 | Moskaluk | Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming. | J Clin Invest | 23778135 |
| 2013 Jul 1 | Futreal,El-Naggar | Whole exome sequencing of adenoid cystic carcinoma. | J Clin Invest | 23778141 |
| 2013 Jul 1 | Chan | The mutational landscape of adenoid cystic carcinoma. | Nat Genet | 23685749 |
| 2011 Jul 1 | El-Naggar | CpG island methylation profiling in human salivary gland adenoid cystic carcinoma. | Cancer | 21692051 |
| 2011 Jul 1 | Ha, Moskaluk | Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma. | Clin Cancer Res | 21551254 |
| 2011 Jul 1 | Stenman | The MYB-NFIB gene fusion-a novel genetic link between adenoid cystic carcinoma and dermal cylindroma. | J Pathol | 21618541 |
| 2015 Jun 5 | Stenman | Detection of MYB Alterations and Other Immunohistochemical Markers in Primary Cutaneous Adenoid Cystic Carcinoma. | Am J Surg Pathol | 26076064 |
| 2015 Jun 3 | El-Naggar | Analysis and significance of c-MET expression in adenoid cystic carcinoma of the salivary gland. | Cancer Biol Ther | 25923130 |
| 2015 Jun 26 | Nor | BH3-mimetic small molecule inhibits the growth and recurrence of adenoid cystic carcinoma. | Oral Oncol | 26121939 |
| 2013 Jun 25 | El-Naggar | MicroRNA profiling of salivary adenoid cystic carcinoma: association of miR-17-92 upregulation with poor outcome. | PLos One | 23825564 |
| 2015 Jun 16 | Dillon, Thomas, Moskaluk | Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials. | Head Neck | 25487882 |
| 2015 Jun 12 | Weigelt, Reis-Filho, Chan, Stenman | Genomic landscape of adenoid cystic carcinoma of the breast. | J Pathol | 26095796 |
| 2016 Jun 1 | Li | Bmi-1 expression predicts prognosis in salivary adenoid cystic carcinoma and correlates with epithelial-mesenchymal transition-related factors. | Ann Diagn Pathol | 27180058 |
| 2015 Jun 1 | Klempnauer | Naphthol AS-E Phosphate Inhibits the Activity of the Transcription Factor Myb by Blocking the Interaction with the KIX Domain of the Coactivator p300. | Mol Cancer Ther | 25740244 |
| 2013 Jun 1 | El-Naggar | Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance. | Am J Pathol. | 23583282 |
| 2010 Jun 1 | Moskaluk, Futreal, El-Naggar | C-kit gene mutations in adenoid cystic carcinoma are rare. | Mod Pathol | 20514080 |
| 2015 May 8 | Weigelt, Reis-Filho | Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing. | Histopathology | 25951887 |
| 2018 May 3 | Ferrarotto | A Phase 1 dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors. | Ann Oncol | 29726923 |
| 2017 May 26 | El-Naggar, Futreal, Mitani | Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma. | J Natl Cancer Inst | 29117356 |
| 2017 May 22 | Stenman, Wick | Targeting the Oncogenic Transcriptional Regulator MYB in Adenoid Cystic Carcinoma by Inhibition of IGF1R/AKT Signaling. | J Natl Cancer Inst | 28954282 |
| 2014 May 22 | Queimado | Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence. | Cell Death Dis. | 24853424 |
| 2016 May 18 | Wong | The impact of the MYB-NFIB fusion protooncogene in vivo. | Oncotarget | 27213588 |
| 2017 May 1 | Ivanov, Yarbrough, Moskaluk | MYB fusions and CD markers as tools for authentication and purification of cancer stem cells from salivary adenoid cystic carcinoma. | Stem Cell Res | 28500913 |
| 2016 May 1 | Ferrarotto | MYB-fusions and other potential actionable targets in adenoid cystic carcinoma. | Curr Opin Oncol | 26974847 |
| 2015 May 1 | Ha | MYB rearrangement and clinicopathologic characteristics in head and neck adenoid cystic carcinoma. | Laryngoscope | 25963073 |
| 2017 Apr 8 | Castilho, Nor | Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence. | Stem Cell Res | 28426972 |
| 2017 Apr 4 | Moskaluk | A Phase II study of Dovitinib in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma. | Clin Cancer Res | 28377480 |
| 2019 Apr 22 | Morris, Chan, Ho | Immunogenic neoantigens derived from gene fusions stimulate T cell responses. | Nat Med | 31011208 |
| 2019 Apr 2 | Ho | Phase II Study of Lenvatinib in Patients With Progressive, Recurrent or Metastatic Adenoid Cystic Carcinoma. | J Clin Oncol | 30939095 |
| 2016 Apr 15 | Ivanov, Yarbrough | NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma. | Clin Cancer Res | 27084744 |
| 2019 Apr 1 | Bakst | Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer. | Int J Radiat Oncol Biol Phys | 30562546 |
| 2015 Apr 1 | Ramsay | MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region. | PLoS One | 25853889 |
| 2014 Apr 1 | Pusztaszeri, Faquin | MYB immunostaining is a useful ancillary test for distinguishing adenoid cystic carcinoma from pleomorphic adenoma in fine-needle aspiration biopsy specimens. | Cancer Cytopathol | 24302647 |
| 2011 Apr 1 | Ha | Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma. | Oral Oncol | 21324728 |
| 2017 Mar 22 | LoRusso, Goncalves | A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma. | Oncotarget | 28415633 |
| 2016 Mar 2 | Nor, Moskaluk, Wick | Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma. | Clin Cancer Res | 26936915 |
| 2018 Mar 19 | Jimeno, Reyland | Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene fusions associated with tumor progression. | Clin Cancer Res | 29555661 |
| 2019 Mar 1 | Moskaluk, Agarwal | Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation. | EBioMedicine | 30765319 |
| 2017 Mar 1 | Wick | A Phase I Clinical Trial and Independent Patient-Derived Xenograft Study of Combined Targeted Treatment with Dacomitinib and Figitumumab in Advanced Solid Tumors. | Clin Cancer Res | 27733479 |
| 2013 Mar 1 | Moskaluk | Adenoid cystic carcinoma: clinical and molecular features. | Head Neck Pathol. | 23463073 |
| 2013 Mar 1 | Stenman | Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations. | Histopathology | 23398044 |
| 2012 Mar 1 | El-Naggar | Developmental transcription factor EN1–a novel biomarker in human salivary gland adenoid cystic carcinoma. | Cancer | 21800291 |
| 2025 Jan 11 | Izumchenko, Agrawal, Pearson | PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands | J Exp Clin Cancer Res | 39794830 |
| 2024 Dec 6 | Pelaez | Circulating Adenoid Cystic Carcinoma associated MYB transcripts enable rapid and sensitive detection of metastatic disease in blood liquid biopsies | J Liq Biopsy | 39801676 |
| 2024 Dec 4 | Chen | Heterogeneous immune landscapes and macrophage dynamics in primary and lung metastatic adenoid cystic carcinoma of the head and neck | Frontiers Immun | 39697346 |
| 2024 Nov 22 | de Sousa, Ferrarotto | B7-H4: A potential therapeutic target in adenoid cystic carcinom | Oncotarget | 39576662 |
| 2024 Nov 1 | Morris | Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort | Mol Diagn Ther. | 39485665 |
| 2024 Oct 26 | Faquin, Fisch, Lennerz, Iafrate, Theirauf | Comparative Analysis of MYB Expression by Immunohistochemistry and RNA Sequencing in Clinical Gene Fusion Detection in Adenoid Cystic Carcinoma | Head Neck Pathol | 39460831 |
| 2024 Oct 1 | Ho, Morris | Phase 2 trial of regorafenib in recurrent or metastatic adenoid cystic carcinoma | Clin Cancer Res | 39352719 |
| 2024 Sep 24 | Doggett | Long-term treatment of metastatic adenoid cystic carcinoma with sequential brachytherapy and stereotactic body radiotherapy | Radiat Oncol J | 39354827 |
| 2024 Sep 3 | Esmaeli, Ferrarotto | Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma | Invest Ophthalmol Vis Sci | 39230995 |
| 2024 Aug 26 | Van Herpen | Lutetium-177-PSMA therapy for recurrent/metastatic salivary gland cancer: a prospective pilot study | Theranostics | 39310108 |
| 2024 Aug 22 | Wirth | Case 26-2024: A 59-Year-Old Woman with Aphasia, Anemia, and a Breast Mass | N Engl J Med | 39167811 |
| 2024 Aug 1 | Zhu | Adenoid Cystic Carcinoma in the Trachea: When Surgery is Not Feasible | International Journal of Radiation Oncology, Biology, Physics | 39038904 |
| 2024 Jul 15 | Karpinets, Mitani, Ferrarotto, Futreal, El-Naggar | Intratumoral microbiome of adenoid cystic carcinomas and comparison with other head and neck cancers. | Sci Rep | 39009605 |
| 2024 Jul 9 | Amelio, Yarbrough, Ferrarotto | Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites | Sci Rep | 38982149 |
| 2024 Jun 11 | Nor, Castilho, Warner | Establishment and characterization of cMYB-expressing human salivary adenoid cystic carcinoma cell lines (UM-HACC-14, UM-HACC-6) and matching patient-derived xenograft model (UM-PDX-HACC-14) | Oral Surg Oral Med Oral Pathol Oral Radiol | 38971694 |
| 2024 May 30 | Ferrarotto, Hoff | Vascular Endothelial Growth Factor Receptor Inhibitors for Recurrent or Metastatic Adenoid Cystic Carcinoma: A Systematic Review and Meta-Analysis | JAMA Otolaryngol Head Neck Surg | 38814585 |
| 2024 Apr 24 | Malheiros Coutinho-Camillo | Molecular Aspects of Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of the Salivary Gland | Head Neck Pathol | 38658430 |
| 2024 Apr 15 | Keam | Analysis of Response and Progression Patterns of Tyrosine Kinase Inhibitors in Recurrent or Metastatic Adenoid Cystic Carcinoma: A Post Hoc Analysis of Two KCSG Phase II Trials | Cancer Res Treat | 38637966 |
| 2024 Apr 1 | Ferrarotto, El-Naggar, de Sousa | First Use of AXL Targeting in Metastatic, Refractory, Adenoid Cystic Carcinoma: A Case Report | JCO Precis Oncol | 38579194 |
| 2024 Apr 1 | Stenman, Andersson, Morris | MYB alternative promoter activity is increased in adenoid cystic carcinoma metastases and is associated with a specific gene expression signature | Oral Oncology | 38493544 |
| 2024 Mar 19 | Ferrarotto, El Naggar | Prognostic value of tumor volume doubling time in lung-metastatic adenoid cystic carcinoma. | Oral Oncol. | 38507991 |
| 2024 Mar 16 | Stenman, Morris | MYB alternative promoter activity is increased in adenoid cystic carcinoma metastases and is associated with a specific gene expression signature | Oral Oncol. | 38493544 |
| 2024 Mar 12 | Klempnauer | Transcription Factor MYB as Therapeutic Target: Current Developments | Int J Mol Sci | 38542205 |
| 2024 Feb 28 | Hanna | Molecular profiling and the impact of treatment on outcomes in adenoid cystic carcinoma (ACC) type-I and II | Clin Cancer Res | 38416410 |
| 2024 Feb 17 | Weigelt | Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements | Gynecol Oncol | 38368814 |
| 2024 Feb 1 | Esmaeli, Ferrarotto | Lacrimal Gland Adenocarcinoma Clinicopathologic Features and Outcomes Compared With Those of Lacrimal Gland Adenoid Cystic Carcinoma | Ophthalmic Plast Reconstr Surg | 38319188 |
| 2024 Jan 29 | Castilho | Novel Epigenetic Modifiers of Histones Presenting Potent Inhibitory Effects on Adenoid Cystic Carcinoma Stemness and Invasive Properties | Int J Mol Sci | 38338924 |
| 2023 Dec 19 | A. Sala, G. Sala, Stenman | The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma | FEBS Lett | 38112379 |
| 2023 Dec 19 | Ferrarotto, Swiecicki, Kung, Hanna | PRT543, a protein arginine methyltransferase 5 inhibitor, in patients with advanced adenoid cystic carcinoma: An open-label, phase I dose-expansion study | Oral Oncol | 38118249 |
| 2023 Nov 20 | Sala, Wick, Spardy Burr | Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma | Oral Oncol | 37988837 |
| 2023 Nov 16 | Pelaez | Apoptotic Marker Expression of Resected Lacrimal Gland Adenoid Cystic Carcinoma Tumor Margins After Intra-arterial Chemotherapy and Globe-Sparing Excision | Ophthalmic Plast Reconstr Surg | 37972978 |
| 2023 Nov 16 | Faquin | Second edition of the Milan System for Reporting Salivary Gland Cytopathology: Refining the role of salivary gland FNA | Cytopathology | 37971186 |
| 2023 Oct 28 | Ferrarotto, El-Naggar, Mitani, de Sousa, | Analysis of B7-H4 Expression Across Salivary Gland Carcinomas Reveals Adenoid Cystic Carcinoma-Specific Prognostic Relevance | Mod Pathol | 38015043 |
| 2023 Oct 13 | Keam | Artificial intelligence-powered spatial analysis of tumor-infiltrating lymphocytes as a predictive biomarker for axitinib in adenoid cystic carcinoma | Head Neck | 37828867 |
| 2023 Oct 1 | Hansen, Siu, Hernando-Calvo | Selinexor for the treatment of recurrent or metastatic salivary gland tumors: Results from the GEMS-001 clinical trial | Cancer Med | 37818869 |
| 2023 Sep 14 | Hanna, Keam | A Phase I Study of the Pan-Notch Inhibitor CB-103 for Patients with Advanced Adenoid Cystic Carcinoma and Other Tumors | Cancer Res Commun | 37712875 |
| 2023 Aug 29 | Kang, Hanna, Ho, Keam | A Phase 2 Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma | Clin Cancer Res | 37643133 |
| 2023 Aug 24 | Morris, Ho, Chan | Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial | Nat Med | 37620627 |
| 2023 Aug 22 | Metcalf, Aster | Gene expression patterns in adenoid cystic carcinoma with and without diffuse NOTCH1 intracellular domain (NICD1) immunohistochemistry staining | Oral Oncol | 37619521 |
| 2023 Aug 14 | Kiess | PSMA-targeted therapy for non-prostate cancers | Front Oncol | 37645427 |
| 2023 Aug 11 | Stenman, El-Naggar, Ferrarotto, Moskaluk, Frierson, Mitani | Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers | J Pathol | 37565350 |
| 2023 Jul 31 | Goncalves, LoRusso | A pilot study of volumetric and density tumor analysis of ACC patients treated with vorinostat in a phase II clinical trial | Heliyon | 37593628 |
| 2023 Jul 6 | Dalerba, Moskaluk | Inverse agonists of retinoic acid receptor/retinoid X receptor signaling as lineage-specific antitumor agents against human adenoid cystic carcinoma | J Natl Cancer Inst | 37040084 |
| 2023 Jun 19 | Pelaez | Mass spectrometry database of lacrimal gland adenoid cystic carcinoma and normal lacrimal gland tissue identifies extracellular matrix remodeling in these tumors | Data Brief | 37409171 |
| 2023 May 31 | Ferrarotto, El-Naggar, de Sousa, Mitani, Bell, Spardy Burr | Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors | Clin Cancer Res | 37256648 |
| 2023 May 31 | Nor | Therapeutic inhibition of Bmi-1 ablates chemoresistant cancer stem cells in adenoid cystic carcinoma | Oral Oncol | 37267716 |
| 2023 Mar 10 | Ferrarotto, El-Naggar, Bell, Mithani | Phase II Clinical Trial of Axitinib and Avelumab in Patients With Recurrent/Metastatic Adenoid Cystic Carcinoma | J Clin Oncol | 36898078 |
| 2023 Mar 6 | Chen | Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway | Exp Mol Med | 36879115 |
| 2023 Feb 22 | Ness, El-Naggar, Andreasen, Pelaez | Dominant Gene Expression Profiles Define Adenoid Cystic Carcinoma (ACC) from Different Tissues: Validation of a Gene Signature Classifier for Poor Survival in Salivary Gland ACC | Cancers | 36900183 |
| 2023 Feb 3 | Zhu | Combined all-trans retinoic acid with low-dose apatinib in treatment of recurrent/metastatic head and neck adenoid cystic carcinoma: A single-center, secondary analysis of a phase II study | Cancer Med | 36734294 |
| 2023 Jan 31 | Bossi | Functional profiles of curatively treated adenoid cystic carcinoma unveil prognostic features and potentially targetable pathways | 36720951 | |
| 2023 Jan 15 | Castilho, Goncalves, Wick | Using PDX animal models to identify and stratify adenoid cystic carcinoma patients presenting an enhanced response to HDAC inhibitors | Am J Cancer Res | 36777521 |
| 2023 Jan 13 | Hanna | Systemic and Targeted Therapies in Adenoid Cystic Carcinoma | Curr Treat Options Oncol | 36637743 |
| 2022 Dec 16 | Chen | High-risk subtype: Clinical manifestations and molecular characteristics of submandibular gland adenoid cystic carcinoma | Front Oncol | 36591454 |
| 2022 Nov 29 | Bernstein, Faquin, Lin, Deschler, Aster | Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma | Cell Rep | 36450256 |
| 2022 Nov 22 | Bingle, Ferrarotto | Drug-based therapy for advanced adenoid cystic carcinoma: current landscape and challenges based on an overview of registered clinical trials | Crit Rev Oncol Hematol | 36427771 |
| 2022 Nov 20 | Kang, Ha | Approaches to the Management of Metastatic Adenoid Cystic Carcinoma | Cancers | 36428790 |
| 2022 Nov 17 | Chen | Single-cell transcriptomic analysis of the tumor ecosystem of adenoid cystic carcinoma | Front Oncol | 36465348 |
| 2022 Oct 18 | van Herpen | Development and characterization of patient-derived salivary gland cancer organoid cultures | Oral Oncol | 36265373 |
| 2022 Aug 27 | van Herpen | Identification of Fusion Genes and Targets for Genetically Matched Therapies in a Large Cohort of Salivary Gland Cancer Patients | Cancers (Basel) | 36077692 |
| 2022 Aug 19 | Chen | A pilot study of 68 Ga-PSMA-617 PET/CT imaging and 177 Lu-EB-PSMA-617 radioligand therapy in patients with adenoid cystic carcinoma | EJNMMI | 35984529 |
| 2022 Aug 13 | Castilho, Nor | Adenoid Cystic Carcinoma from the salivary and lacrimal glands and the breast: different clinical outcomes to the same tumor | Crit Rev Oncol Hematol | 35973662 |
| 2022 Aug 8 | Metcalf | Clinical disease course and survival outcomes following disease recurrence in adenoid cystic carcinoma with and without NOTCH signaling pathway activation | Oral Oncology | 35952580 |
| 2022 Aug 7 | Chen | Prognosis of adenoid cystic carcinoma of head and neck and risk factors for lung metastasis | Zhonghua | 36058663 |
| 2022 Aug 5 | Ferrarotto, Izumchenko, Agrawal, Aster | AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling | Cell Death and Disease | 35931701 |
| 2022 Jul 28 | Stenman, El-Naggar, Moskaluk, Ferrarotto, Frierson, Mitani | Rearrangements, Expression, and Clinical Significance of MYB and MYBL1 in Adenoid Cystic Carcinoma: A Multi-Institutional Study | Cancers | 35954356 |
| 2022 Jul 19 | Ferrarotto, de Sousa | Metastatic Adenoid Cystic Carcinoma: Genomic Landscape and Emerging Treatments | Curr Treat Options Oncol | 35854180 |
| 2022 Jun 20 | Bingle | MYB-NFIB fusion transcript in adenoid cystic carcinoma: Current state of knowledge and future directions | Crit Rev Onc Hematol | 35738530 |
| 2022 Jun 6 | Faquin, Deschler | Multiplexed single-cell analysis of FNA allows accurate diagnosis of salivary gland tumors | Cancer Cytopathol | 35666645 |
| 2022 Jun 4 | Baujat, Atallah | Beyond Surgical Treatment in Adenoid Cystic Carcinoma of the Head and Neck: A Literature Review | Cancer Manag Res | 35693117 |
| 2022 Apr 30 | Ha, Morris | Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma | Cancers (Basel) | 35565392 |
| 2022 Feb 25 | Ferrarotto | Treatment of Recurrent or Metastatic Adenoid Cystic Carcinoma | Curr Oncol Rep | 35212920 |
| 2022 Feb 23 | Metcalf | Evaluation of the Clinical Utility of Genomic Profiling to Inform Selection of Clinical Trial Therapy in Salivary Gland Cancer | Cancers (Basel) | 35267442 |
| 2022 Feb 1 | van Herpen | 68Ga-Prostate-Specific Membrane Antigen-Avid Malignant Pleural Effusion in a Patient With Metastatic Adenoid Cystic Carcinoma and Concordance With 18F-FDG PET/CT | Clin Nucl Med | 35006109 |
| 2021 Dec 19 | Schoenfeld, Hanna, Chau | Oligometastatic adenoid cystic carcinoma: Correlating tumor burden and time to treatment with outcomes | Head Neck | 34927307 |
| 2021 Dec 17 | Bakst | Radiation Therapy for Adenoid Cystic Carcinoma of the Head and Neck | Cancers | 34944955 |
| 2021 Dec 14 | van Herpen | Excessive toxicity of cabozantinib in a phase II study in patients with recurrent and/or metastatic salivary gland cancer | Eur J Cancer | 34920917 |
| 2021 Nov 1 | Klempnauer, Stenman | Proteasome inhibitors suppress MYB oncogenic activity in a p300-dependent manner | Cancer Lett | 34256093 |
| 2021 Oct 29 | Doggett | CT-guided palladium-103 seed brachytherapy for metastatic adenoid cystic carcinoma: a retrospective study to assess initial safety and effectiveness of percutaneous CT fluoroscopy-guided permanent seed brachytherapy | J Contemp Brachytherapy | 34759974 |
| 2021 Oct 1 | Reis-Filho, Weigelt | The clinical behavior and genomic features of the so-called adenoid cystic carcinomas of the solid variant with basaloid features | Mod Pathol | Nature |
| 2021 Sep 22 | Mapp | A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb | J Am Chem Soc | 34491719 |
| 2021 Sep 15 | Nor | Systemic therapies for salivary gland adenoid cystic carcinoma | Am J Cancer Res | 34659878 |
| 2021 Sep 6 | Zhu | The Immune Landscape of Chinese Head and Neck Adenoid Cystic Carcinoma and Clinical Implication | Frontiers Immunology | 34552580 |
| 2021 Aug 27 | Metcalf | Centralised RECIST Assessment and Clinical Outcomes with Lenvatinib Monotherapy in Recurrent and Metastatic Adenoid Cystic Carcinoma | Cancers | 34503145 |
| 2021 Jul 27 | Keam | Randomized phase II study of axitinib versus observation in patients with recurred or metastatic adenoid cystic carcinoma | Clin Cancer Res | 34315722 |
| 2021 Jul 15 | El-Naggar, Karpinets, Futreal, Ferrarotto, Mitani | Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations | Clin Cancer Res | 34011559 |
| 2021 Jun 12 | van Herpen | PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports | Eur J Nucl Med Mol Imaging | 34120192 |
| 2021 Jun 10 | Ha, Swiecicki, Deschler, Chau, Kaufman | Management of Salivary Gland Malignancy: ASCO Guideline | J Clin Oncol | 33900808 |
| 2021 Jun 3 | Hanna, Zon, Wirth, Park, Haddad, Lohr, Spardy Burr, Kaufman | A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma | Oral Oncol | 34091189 |
| 2021 Jun 1 | Esmaeli, El-Naggar, Ferrarotto, Bell | Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma | Br J Ophthalmol | 32680839 |
| 2021 Apr 1 | Ha | MYB RNA In Situ Hybridization Facilitates Sensitive and Specific Diagnosis of Adenoid Cystic Carcinoma Regardless of Translocation Status | Am J Surg Pathol | 33165092 |
| 2021 Feb 26 | Sala | MYB oncoproteins: emerging players and potential therapeutic targets in human cancer | Oncogenesis | 33637673 |
| 2021 Feb 15 | Ha, Kang, Fertig, Keam | Newly Identified Members of FGFR1 Splice Variants Engage in Cross-talk with AXL/AKT Axis in Salivary Adenoid Cystic Carcinoma | Cancer Res | 33408119 |
| 2021 Feb 1 | Metcalf | The utility of TP53 and PIK3CA mutations as prognostic biomarkers in salivary adenoid cystic carcinoma | Oral Oncol | 33290961 |
| 2020 Nov 10 | El-Naggar, Ferrarotto, Mitani, Futreal, Aster, Bell, Karpinets | Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets | Clin Cancer Res | 33172898 |
| 2020 Nov 5 | Ha | MYB RNA In Situ Hybridization Facilitates Sensitive and Specific Diagnosis of Adenoid Cystic Carcinoma Regardless of Translocation Status | Am J Surg Pathol | 33165092 |
| 2020 Oct 1 | Lin | Adenoid Cystic Carcinoma of the Skull Base: Response to Radiation Therapy and Outcomes in a Retrospective Case Series | J Neurol Surg B Skull Base | 33134017 |
| 2020 Sep 28 | Seiwert, Kiess | Time to Debunk an Urban Myth? The “Abscopal Effect” With Radiation and Anti–PD-1 | J Clin Oncol | 32986527 |
| 2020 Sep 1 | van Herpen | 68Ga-Prostate-Specific Membrane Antigen-11-Avid Cardiac Metastases in a Patient With Adenoid Cystic Carcinoma, A Rare Presentation of a Rare Cancer | Clin Nucl Med | 32701807 |
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