Project List
The table below lists the most significant projects coordinated and/or funded by ACCRF.
Projects Coordinated and/or Funded by ACCRF
Investigator Institution Research Project SPECIMENS & MODELS El-Naggar, Adel MD Anderson Biobanking and model development Ha, Patrick Johns Hopkins U Deriving ACC cell lines from xenograft explants Ince, Tan U of Miami Development of an in vitro culture system for primary ACC cells Moskaluk, Christopher U of Virginia Biobanking and model development Moyer, Mary Pat INCELL Culture and characterization of ACC cell lines NA NIDCR Salivary gland tumor research initiatives Queimado, Lurdes U of Oklahoma Establishment of ACC stem cell lines Wick, Michael START Development, propagation, amplification and maintenance of human ACC models TARGET AND PATHWAY IDENTIFICATION Basile, John U of Maryland Perineural invasion in ACC Bender, Timothy U of Virginia c-Myb/NFIB fusion proteins in ACC Bernstein, Bradley Mass General Investigating the role of MYB translocation on the chromatin landscape in ACC Brandwein-Gensler, Margaret U of Alabama Transcriptionally active human papillomavirus infection and ACC El-Naggar, Adel MD Anderson MYB-NFIB fusion gene and genomic screening of ACCs El-Naggar, Adel MD Anderson Genomic studies of ACC Futreal, Andy Sanger Institute ACC pilot sequencing project Futreal, Andy Sanger Institute Comprehensive investigation of ACC somatic genetics Gonda, Tom U of Queensland A retroviral transduction and transplantation model of ACC and its application to targeting MYB-NFIB Gu, Ting-Lei Cell Signaling Tech Phosphoproteomic analysis of tyrosine kinases in primary and xenografted ACC tumors Ha, Patrick Johns Hopkins U Integrated, array-based screening for tumor suppressor genes in ACC primary tumor xenografts Harlow, Ed Harvard University shRNA screen to identify essential kinases in ACC Kirsch, Claudia UCLA Sensitivity of 3T MRIs and radiologic differentiation of ACC patients Moskaluk, Christopher U of Virginia ACC disease pathway analysis Ness, Scott U of New Mexico Activities of c-Myb variants expressed in ACC Nor, Jacques U of Michigan Stem cells in ACC Papin, Jason U of Virginia Bioinformatics systems biology approaches for ACC Stenman, Goran U of Gothenburg Characterization of genomic imbalances in ACC using high-resolution oligonucleotide array CGH Stenman, Goran U of Gothenburg Studies of a novel fusion oncogene in ACC Stenman, Goran U of Gothenburg Studies of genomic deletions and receptor tyrosine kinases as targets for therapy in ACC Wong, Kwok Dana-Farber Determine the impact of MYB-NFIB fusion in de novo ACC tumorigenesis in mice Yarbrough, Dell Vanderbilt The role of neurotrophic signaling in ACC Zhu, Naishuo Fudan U The characteristics of ACC metastasis-related gene function TRANSLATIONAL RESEARCH Wick, Michael START In vivo evaluation of the human ACC models with various anticancer agents in immunocompromised mice LoRusso, Pat Karmanos Correlative studies for Phase 2 study of SAHA in subjects with advanced ACC Zon, Len Harvard University Finding chemicals that suppress c-MYB expression Download Projects Coordinated and/or Funded by ACCRF
